pbs-ii proteinchip reader (Ciphergen inc)
90
Structured Review
Ciphergen inc
pbs-ii proteinchip reader
Pbs Ii Proteinchip Reader, supplied by Ciphergen inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pbs-ii+proteinchip+reader/pbs+ii+proteinchip+reader/pmc02761863-257-6-9
Average 90 stars, based on 1 article reviews
Pbs Ii Proteinchip Reader, supplied by Ciphergen inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pbs-ii+proteinchip+reader/pbs+ii+proteinchip+reader/pmc02761863-257-6-9
Average 90 stars, based on 1 article reviews
pbs-ii proteinchip reader - by Bioz Stars,
2026-10
90/100 stars
Images
1) Product Images from "Discovery and identification of potential biomarkers of papillary thyroid carcinoma"
Article Title: Discovery and identification of potential biomarkers of papillary thyroid carcinoma
Journal: Molecular Cancer
doi: 10.1186/1476-4598-8-79
Figure Legend Snippet: Representative spectra from ProteinChip array with specific immobilized antibodies . (A) Representative spectra of the negative control (nonspecific rabbit IgG). (B) Representative spectra from ProteinChip array with anti-haptoglobin alpha chain antibody. (C) Representative spectra from ProteinChip array with anti-apolipoprotein C-I. (D) Representative spectra from ProteinChip array with anti-apolipoprotein C-III.
Techniques Used: Negative Control
Related Articles
Negative Control:Article Title: A unique proteolytic fragment of alpha1-antitrypsin is elevated in ductal fluid of breast cancer patient. Article Snippet: By comparison of mass spectra from a small cohort of nipple aspiration fluids (NAF), we previously discovered a panel of five candidate breast cancer biomarkers among them an unidentified 4.7 kD peptide BF5.. The purposes of the present study were to verify the presence of BF5 in an independent cohort; to determine the protein identity of BF5; and to provide insight into the biology of BF5 production and elevation in tumor-associated NAF.. We prospectively collected bilaterally matched NAF from patients with unilateral Stage I/II breast cancer (IBC-31), ductal carcinoma in situ (DCIS-6), atypical ductal hyperplasia (ADH-5), and presumed healthy women who came to routine mammography and had a normal exam (31). Article Title: HLA homology within the C5 domain promotes peptide binding by HIV type 1 gp120. Article Snippet: The mechanisms by which HIV-1 induces chronic pathogenic immune activation associated with disease progression remain unclear despite many years of AIDS research.. One proposal suggests that sequence and structural mimicry between gp120 and HLA may endow HIV with the capacity to arouse alloreactive and autoimmune responses within the susceptible host, fueling disease progression in a manner similar to graft-versus-host disease (GVHD).. Both gp120 and HLA share a common functional interaction with CD4 but also demonstrate peptide binding properties. Article Title: Identification of serum protein markers for breast cancer relapse with SELDI-TOF MS. Article Snippet: MS analysis was performed on a PBS-II ProteinChip reader (Ciphergen Biosystems). Article Title: Toward the proteomic identification of biomarkers for the prediction of HBV related hepatocellular carcinoma. Article Snippet: Early detection is a key step for effective intervention of hepatocellular carcinoma (HCC), the lack of sensitive and specific biomarkers is a major reason for the high rate of HCC-related mortality.. This report described an integrated strategy by combining SELDI-ProteinChip, sophisticated algorithm analysis, acetonitrile (ACN) pre-treatment and two-dimensional electrophoresis (2DE)–peptide mass fingerprinting (PMF) techniques to identify serological markers for the prediction of HBV-related HCC.. Proteomic profiling of three groups of serum specimens from HBV-related HCC (50 cases), HBV infection (45 cases), and normal subjects (30 cases) was conducted by using SELDI-ProteinChip system and the resulting different protein peaks were subjected to stepwise statistical analyses. Article Title: Regulation of CXCR/IL-8 in human airway epithelial cells. Article Snippet: Background: Severe asthma is characterized by neutrophilic inflammation and high levels of interleukin (IL)-8.. Airway epithelial cells play a pivotal role in the pathogenesis and chronicity of asthma.. The objective of this work was to determine whether CXC receptors were involved in human small airway epithelial cell (SAEC) activity by incubating them with IL-8; the investigation also included a proteomic approach. Article Title: Biomarkers for breast cancer Article Snippet: Proteins bound to the chip surfaces were detected with a PBS-II ProteinChip Reader (Ciphergen Biosystems, CA). Article Title: Discovery and identification of potential biomarkers of papillary thyroid carcinoma Article Snippet: MS analysis was performed on a PBS-II ProteinChip reader (Ciphergen Biosystems). Article Title: A combined biomarker pattern improves the discrimination of lung cancer Article Snippet: A total of 227 sera were analysed using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to find novel serum biomarkers for lung cancer.. The results showed that the 11.53, 11.70, 13.78, 13.90 and 14.07 k m/z peaks identified as native serum amyloid A (SAA), SAA with N-terminal Arg cleaved, native transthyretin (TTR) and its two variants significantly differentiated lung cancer sera from normal control sera (p <0.01).. A ‘biomarker pattern’ combining SAA and TTR was tested to distinguish lung cancer patients from normal control individuals, and the diagnostic positive rate of lung cancer was improved to 91.6%. Blocking Assay:Article Title: A unique proteolytic fragment of alpha1-antitrypsin is elevated in ductal fluid of breast cancer patient. Article Snippet: By comparison of mass spectra from a small cohort of nipple aspiration fluids (NAF), we previously discovered a panel of five candidate breast cancer biomarkers among them an unidentified 4.7 kD peptide BF5.. The purposes of the present study were to verify the presence of BF5 in an independent cohort; to determine the protein identity of BF5; and to provide insight into the biology of BF5 production and elevation in tumor-associated NAF.. We prospectively collected bilaterally matched NAF from patients with unilateral Stage I/II breast cancer (IBC-31), ductal carcinoma in situ (DCIS-6), atypical ductal hyperplasia (ADH-5), and presumed healthy women who came to routine mammography and had a normal exam (31). Article Title: HLA homology within the C5 domain promotes peptide binding by HIV type 1 gp120. Article Snippet: The mechanisms by which HIV-1 induces chronic pathogenic immune activation associated with disease progression remain unclear despite many years of AIDS research.. One proposal suggests that sequence and structural mimicry between gp120 and HLA may endow HIV with the capacity to arouse alloreactive and autoimmune responses within the susceptible host, fueling disease progression in a manner similar to graft-versus-host disease (GVHD).. Both gp120 and HLA share a common functional interaction with CD4 but also demonstrate peptide binding properties. Article Title: Identification of serum protein markers for breast cancer relapse with SELDI-TOF MS. Article Snippet: MS analysis was performed on a PBS-II ProteinChip reader (Ciphergen Biosystems). Article Title: Toward the proteomic identification of biomarkers for the prediction of HBV related hepatocellular carcinoma. Article Snippet: Early detection is a key step for effective intervention of hepatocellular carcinoma (HCC), the lack of sensitive and specific biomarkers is a major reason for the high rate of HCC-related mortality.. This report described an integrated strategy by combining SELDI-ProteinChip, sophisticated algorithm analysis, acetonitrile (ACN) pre-treatment and two-dimensional electrophoresis (2DE)–peptide mass fingerprinting (PMF) techniques to identify serological markers for the prediction of HBV-related HCC.. Proteomic profiling of three groups of serum specimens from HBV-related HCC (50 cases), HBV infection (45 cases), and normal subjects (30 cases) was conducted by using SELDI-ProteinChip system and the resulting different protein peaks were subjected to stepwise statistical analyses. Article Title: Regulation of CXCR/IL-8 in human airway epithelial cells. Article Snippet: Background: Severe asthma is characterized by neutrophilic inflammation and high levels of interleukin (IL)-8.. Airway epithelial cells play a pivotal role in the pathogenesis and chronicity of asthma.. The objective of this work was to determine whether CXC receptors were involved in human small airway epithelial cell (SAEC) activity by incubating them with IL-8; the investigation also included a proteomic approach. Article Title: Biomarkers for breast cancer Article Snippet: Proteins bound to the chip surfaces were detected with a PBS-II ProteinChip Reader (Ciphergen Biosystems, CA). Article Title: Discovery and identification of potential biomarkers of papillary thyroid carcinoma Article Snippet: MS analysis was performed on a PBS-II ProteinChip reader (Ciphergen Biosystems). Article Title: A combined biomarker pattern improves the discrimination of lung cancer Article Snippet: A total of 227 sera were analysed using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to find novel serum biomarkers for lung cancer.. The results showed that the 11.53, 11.70, 13.78, 13.90 and 14.07 k m/z peaks identified as native serum amyloid A (SAA), SAA with N-terminal Arg cleaved, native transthyretin (TTR) and its two variants significantly differentiated lung cancer sera from normal control sera (p <0.01).. A ‘biomarker pattern’ combining SAA and TTR was tested to distinguish lung cancer patients from normal control individuals, and the diagnostic positive rate of lung cancer was improved to 91.6%. Biomarker Assay:Article Title: A unique proteolytic fragment of alpha1-antitrypsin is elevated in ductal fluid of breast cancer patient. Article Snippet: By comparison of mass spectra from a small cohort of nipple aspiration fluids (NAF), we previously discovered a panel of five candidate breast cancer biomarkers among them an unidentified 4.7 kD peptide BF5.. The purposes of the present study were to verify the presence of BF5 in an independent cohort; to determine the protein identity of BF5; and to provide insight into the biology of BF5 production and elevation in tumor-associated NAF.. We prospectively collected bilaterally matched NAF from patients with unilateral Stage I/II breast cancer (IBC-31), ductal carcinoma in situ (DCIS-6), atypical ductal hyperplasia (ADH-5), and presumed healthy women who came to routine mammography and had a normal exam (31). Article Title: HLA homology within the C5 domain promotes peptide binding by HIV type 1 gp120. Article Snippet: The mechanisms by which HIV-1 induces chronic pathogenic immune activation associated with disease progression remain unclear despite many years of AIDS research.. One proposal suggests that sequence and structural mimicry between gp120 and HLA may endow HIV with the capacity to arouse alloreactive and autoimmune responses within the susceptible host, fueling disease progression in a manner similar to graft-versus-host disease (GVHD).. Both gp120 and HLA share a common functional interaction with CD4 but also demonstrate peptide binding properties. Article Title: Identification of serum protein markers for breast cancer relapse with SELDI-TOF MS. Article Snippet: MS analysis was performed on a PBS-II ProteinChip reader (Ciphergen Biosystems). Article Title: Toward the proteomic identification of biomarkers for the prediction of HBV related hepatocellular carcinoma. Article Snippet: Early detection is a key step for effective intervention of hepatocellular carcinoma (HCC), the lack of sensitive and specific biomarkers is a major reason for the high rate of HCC-related mortality.. This report described an integrated strategy by combining SELDI-ProteinChip, sophisticated algorithm analysis, acetonitrile (ACN) pre-treatment and two-dimensional electrophoresis (2DE)–peptide mass fingerprinting (PMF) techniques to identify serological markers for the prediction of HBV-related HCC.. Proteomic profiling of three groups of serum specimens from HBV-related HCC (50 cases), HBV infection (45 cases), and normal subjects (30 cases) was conducted by using SELDI-ProteinChip system and the resulting different protein peaks were subjected to stepwise statistical analyses. Article Title: Regulation of CXCR/IL-8 in human airway epithelial cells. Article Snippet: Background: Severe asthma is characterized by neutrophilic inflammation and high levels of interleukin (IL)-8.. Airway epithelial cells play a pivotal role in the pathogenesis and chronicity of asthma.. The objective of this work was to determine whether CXC receptors were involved in human small airway epithelial cell (SAEC) activity by incubating them with IL-8; the investigation also included a proteomic approach. Article Title: Biomarkers for breast cancer Article Snippet: Proteins bound to the chip surfaces were detected with a PBS-II ProteinChip Reader (Ciphergen Biosystems, CA). Article Title: Discovery and identification of potential biomarkers of papillary thyroid carcinoma Article Snippet: MS analysis was performed on a PBS-II ProteinChip reader (Ciphergen Biosystems). Article Title: A combined biomarker pattern improves the discrimination of lung cancer Article Snippet: A total of 227 sera were analysed using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to find novel serum biomarkers for lung cancer.. The results showed that the 11.53, 11.70, 13.78, 13.90 and 14.07 k m/z peaks identified as native serum amyloid A (SAA), SAA with N-terminal Arg cleaved, native transthyretin (TTR) and its two variants significantly differentiated lung cancer sera from normal control sera (p <0.01).. A ‘biomarker pattern’ combining SAA and TTR was tested to distinguish lung cancer patients from normal control individuals, and the diagnostic positive rate of lung cancer was improved to 91.6%. Software:Article Title: A unique proteolytic fragment of alpha1-antitrypsin is elevated in ductal fluid of breast cancer patient. Article Snippet: By comparison of mass spectra from a small cohort of nipple aspiration fluids (NAF), we previously discovered a panel of five candidate breast cancer biomarkers among them an unidentified 4.7 kD peptide BF5.. The purposes of the present study were to verify the presence of BF5 in an independent cohort; to determine the protein identity of BF5; and to provide insight into the biology of BF5 production and elevation in tumor-associated NAF.. We prospectively collected bilaterally matched NAF from patients with unilateral Stage I/II breast cancer (IBC-31), ductal carcinoma in situ (DCIS-6), atypical ductal hyperplasia (ADH-5), and presumed healthy women who came to routine mammography and had a normal exam (31). Article Title: HLA homology within the C5 domain promotes peptide binding by HIV type 1 gp120. Article Snippet: The mechanisms by which HIV-1 induces chronic pathogenic immune activation associated with disease progression remain unclear despite many years of AIDS research.. One proposal suggests that sequence and structural mimicry between gp120 and HLA may endow HIV with the capacity to arouse alloreactive and autoimmune responses within the susceptible host, fueling disease progression in a manner similar to graft-versus-host disease (GVHD).. Both gp120 and HLA share a common functional interaction with CD4 but also demonstrate peptide binding properties. Article Title: Identification of serum protein markers for breast cancer relapse with SELDI-TOF MS. Article Snippet: MS analysis was performed on a PBS-II ProteinChip reader (Ciphergen Biosystems). Article Title: Toward the proteomic identification of biomarkers for the prediction of HBV related hepatocellular carcinoma. Article Snippet: Early detection is a key step for effective intervention of hepatocellular carcinoma (HCC), the lack of sensitive and specific biomarkers is a major reason for the high rate of HCC-related mortality.. This report described an integrated strategy by combining SELDI-ProteinChip, sophisticated algorithm analysis, acetonitrile (ACN) pre-treatment and two-dimensional electrophoresis (2DE)–peptide mass fingerprinting (PMF) techniques to identify serological markers for the prediction of HBV-related HCC.. Proteomic profiling of three groups of serum specimens from HBV-related HCC (50 cases), HBV infection (45 cases), and normal subjects (30 cases) was conducted by using SELDI-ProteinChip system and the resulting different protein peaks were subjected to stepwise statistical analyses. Article Title: Regulation of CXCR/IL-8 in human airway epithelial cells. Article Snippet: Background: Severe asthma is characterized by neutrophilic inflammation and high levels of interleukin (IL)-8.. Airway epithelial cells play a pivotal role in the pathogenesis and chronicity of asthma.. The objective of this work was to determine whether CXC receptors were involved in human small airway epithelial cell (SAEC) activity by incubating them with IL-8; the investigation also included a proteomic approach. Article Title: Biomarkers for breast cancer Article Snippet: Proteins bound to the chip surfaces were detected with a PBS-II ProteinChip Reader (Ciphergen Biosystems, CA). Article Title: Discovery and identification of potential biomarkers of papillary thyroid carcinoma Article Snippet: MS analysis was performed on a PBS-II ProteinChip reader (Ciphergen Biosystems). Article Title: A combined biomarker pattern improves the discrimination of lung cancer Article Snippet: A total of 227 sera were analysed using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) to find novel serum biomarkers for lung cancer.. The results showed that the 11.53, 11.70, 13.78, 13.90 and 14.07 k m/z peaks identified as native serum amyloid A (SAA), SAA with N-terminal Arg cleaved, native transthyretin (TTR) and its two variants significantly differentiated lung cancer sera from normal control sera (p <0.01).. A ‘biomarker pattern’ combining SAA and TTR was tested to distinguish lung cancer patients from normal control individuals, and the diagnostic positive rate of lung cancer was improved to 91.6%. |
